With the price of pure essence high, and nature runes low, the profit is nowhere near what it used to be. However, because of the update where players gradually get more runes per run, I get an average of 11 extra runes per run. So...
215*53 - 130*42 = Approximately 6k profit per run. Of course, we have to take out the costs of duelling rings, and graahks, so this is more like 5k profit per run.
A run take an average of 60 seconds I would say, making a profit of about 300-400kgp per hour.
Not too bad, all things considered. 22kxp/hr too.
After rc it's either 80 con, or 80 mining.